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Methylphenidate Treatment for Severe ADHD in a Bone Marrow Transplant Child with DiGeorge?s Anomaly

Osman Sabuncuošlu, Ferhan Karademir, Meral Berkem.

Abstract
As the number of bone marrow transplantations (BMT) performed in
the pediatric age group is on the rise, there is a growing need to
expand our knowledge of psychopharmacological interventions in
this special situation. We report a case who had undergone BMT for
congenital immunodeficiency syndrome involving thymus aplasia. He
was referred to the child psychiatry department with severe
hyperactivity and mental retardation. Taking the necessary medical
precautions, methylphenidate was started and continued for over a
year. Marked improvement in the symptoms of attention deficit
hyperactivity disorder (ADHD) and better adaptation to his educational
setting were achieved. No adverse event occurred with regard to his
vulnerable immune system.

Key words: methylphenidate, immune system, bone marrow transplantation, immunodeficiency, attention-deficit with hyperactivity disorder (ADHD)



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