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Fentanyl dependence caused by the non-medical use: a case report

Omer Gecici, Zehra Gokmen, Melike Nebioglu.

Abstract
Fentanyl is a pure and selective μ opioid receptor agonist. Its analgesic potency is 80-800 times greater than that of morphine with fewer adverse effects. Available formulations of fentanyl patches in Turkey contain 1.25, 2.5, 5, and 7.5 mg or 10 mg of fentanyl and provide a dose of 12.5?100 lg⁄h for up to 72 h. Abuse of fentanyl patches has been ıncreasingly reported along with different routes of administration such as oral-transmural, intravenous, inhalation, and rectal use. There are many case reports about complications of fentanyl patches because of misuse or abuse. However, this is the first case from Turkey reporting fentanyl dependency in a 59 year old male patient, who had started to use fentanyl without any medical indication. Although abuse of fentanyl is commonly reported, patients should be carefully scrutinized for fentanyl dependence as well.

Key words: Fentanyl, opioid, dependence



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