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Natl J Integr Res Med. 2012; 3(5): 69-73


Sero Prevalence of C.trachomatis in Patient of Bad Obstetric History (BOH)

Dharsandia MV*, Mangukiya JD**, Patel KD**, Soni ST***, Vegad MM****.

Abstract
Background : Bad obstetric history (BOH) implies previous unfavorable fetal outcome. Causes of BOH may be genetic, hormonal, abnormal maternal immune response and maternal infection. C.trachomatis is the most common bacterial sexually transmitted infection worldwide. Also it has been associated with adverse outcomes of pregnancy. The identification of C. trachomatis during pregnancy and its early treatment prior to delivery would therefore be an important strategy to prevent multiple complications in mother. Serology might act as a convenient tool for diagnosis. Methods:139 pregnant patients having history of BOH as study group and 30 normal pregnant as control group were tested by Indirect ELISA for detection of anti C.trachomatis IgM and IgG. Results: Anti C.trachomatis IgM was detected in 21 (15.11%) patients and anti C.trachomatis IgG was detected in 33 (23.74%) patients. Interpretation and Conclusion: Higher numbers of positive patients were found among younger age group. Statistical analysis shows that serological detection of anti C.trachomatis IgM and IgG antibodies for detection of current and past infection by C.trachomatis is significant in BOH patients. [ Dharasandia M et al NJIRM 2012; 3(5) : 69-73]

Key words: BOH, Chlamydia trachomatis, C.trachomatis, IgG, Ig M



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