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Anadolu Psikiyatri Derg. 2013; 14(3): 283-286


Schizo-obsessive disorder in Marfan syndrome

Evrim Özkorumak, Ahmet Tiryaki, Hülya Kılıç Yılmaz, Mevlit İkbal, İsmet Durmuş, Adem Türk.

Abstract
Marfan Syndrome is a connective tissue disorder presenting with multi-organ symptoms. Cases of patients with mental disorders associated with Marfan syndrome was reported previously. We present a case with schizo-obsessive disorder comorbid with Marfan syndrome and literature about this condition will be discussed. Thirty-nine years old, tall female with long limbs and scoliosis referred to psychiatric policlinic with her relatives with complaint of frequent hand washing, anger and doubt against her family and escapes from home. The patient who has delusion of persecution and reference did not have nearly any social activity. The diagnosis of Marfan syndrome was confirmed by history and physical examination with consultation to cardiology, medical genetics, ophthalmology. Although mental diseases associated with Marfan syndrome were documented in literature, Marfan syndrome with schizo-obsessive disorder was not coincided until now. Clinical presentation of a case with burdened family history which was not reported previously is noteworthy.

Key words: Marfan syndrome, schizophrenia, obsessive compulsive disorder



Marfan sendromunda şizo-obsesyon

Özet
Marfan sendromu birçok organ belirtileriyle kendini gösteren bağ doku hastalığıdır. Daha önce Marfan sendromuna eşlik eden ruhsal hastalıklar bildirilmiştir. Bu olguda Marfan sendromuna eşlik eden bir şizo-obsesif bozukluk olgusu sunulacak ve literatür gözden geçirilecektir. Otuz dokuz yaşında, uzun boylu ve uzun eklemli, skolyozu olan kadın hasta psikiyatri polikliniğine sık el yıkama, aileye karşı öfke ve şüphe, evden kaçma yakınmaları ile yakınları eşliğinde başvurmuştur. Aile bireylerine karşı kötülük görme ve alınma sanrıları bulunan hasta hiçbir toplumsal etkinlikte bulunmuyordu. Aileden alınan öykü ve fiziksel muayene sonucu Marfan sendromu tanısı kardiyoloji, genetik, göz konsültasyonları ile doğrulandı. Eşlik eden çeşitli ruhsal hastalıklar literatürde bildirilse bile Marfan sendromu ile birlikte şizo-obsesif bozukluk eş tanısına şu ana kadar rastlanmamıştır. Olgu yüklü aile öyküsü ile daha önce bildirilmemiş bir klinik görünüm bakımından dikkat çekicidir.

Anahtar Kelimeler: Marfan sendromu, şizofreni, obsesif kompulsif bozukluk



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