Present investigation was carried out to analyze effect of safety measures on rate of injuries at two major constructions sites. Study was observational and conducted in two phases. In first phase we have analyzed injured workers for parameters like age, gender, experience, education status, job profile, working hours, work experience, causes and types of injuries. Based on phase one results, we have recommended some suggestions to the site managements and after implementation of these suggestions phase two of this study was done. There were 71 injured workers in phase one while in phase two the rate of injuries reduced by 75% and only 18 workers were injured. Incidences of injuries are high in illiterate (Phase one: 62%; Phase two: 67%), inexperienced (Phase one: 66%; Phase two: 67%), workers working in crafts like labour (Phase one: 56%; Phase two: 39) and mesons (Phase one: 10%; Phase two: 22%). Data from present study indicates that good housekeeping, training, use of certified quality of personal protective device can significantly decreases injuries. Data from phase one study revealed that many injuries were of avoidable nature. Data of second phase showed that implementation of safety measures like good housekeeping, training and use of certified quality of personal protective device can significantly decreases incidences of injuries.