Home|Journals Follow on Twitter| Subscribe to List

Directory for Medical Articles

Open Access


BMMR. 2010; 13(2): 47-50

Immunoadsorption in Highly-Sensitized Kidney Transplant Recipients

Ioannis Griveas, Georgios Visvardis, L Skoura, A Iniotaki, D Papadopoulou, G Sakellariou.

Patients suffering from chronic renal insufficiency, who need to be treated with dialysis, are generally heavily impaired due to the regular, long lasting treatments. One way to escape this si- tuation is renal transplantation. However, patients with multiple blood transfusions or previous preg- nancies are often sensitized, leading to a poor prog- nosis of the immunologic acceptance of the donor organ. To enable even these patients to be trans- planted with an improved prognosis, besides immunosupression, the treatment with procedures of immunoadsorption is a promising therapy option. Four highly sensitized patients were treat- ed with immunoadsorption (2 men/2 women, range of age: 22-49 years). All patients were previously treated with renal transplantation. We noticed sig- nificant reduction in Panel Reactive Antibodies (PRA) from 68% (50%-80%) before the beginning of treatment to 2% (0%-5%) after the end of them. In spite of limited experience, immunoadsorption can safely and effectively remove anti-HLA in End-Stage Renal Failure patients.

Key words: Immunoadsorption, kidney trans- plantation, renal insufficiency

Share this Article

Journal of Behavioral Health


ScopeMed Home
Follow ScopeMed on Twitter
Article Tools
eJPort Journal Hosting
About ScopeMed
License Information
Terms & Conditions
Privacy Policy
Suggest a Journal
Publisher Login
Contact Us

The articles in Scopemed are open access articles licensed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License (https://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.
ScopeMed is a Database Service for Scientific Publications. Copyright ScopeMed Information Services.
Scopemed Buttons