Prevalence of Iron, Folic Acid and Vitamin B12 Deficiency in Patients with Thalassemia MinorSuheyl Asma, Cigdem Gereklioglu, Ahmet Ferit Erdogan, Mahmut Yeral, Mutlu Kasar, Can Boga, Hakan Özdogu.
Thalassemia trait (TT)-related anemia is a common hematologic problem in Mediterranean region. This type of anemia may be frequently confused with iron deficiency anemia (IDA). Anemia becomes more severe in case of co-existence of both anemia types. This study was carried out with the aim of investigation of iron, folic acid and vitamin B12 levels in patients who were diagnosed with beta thalassemia minor. A total of 183 patients (47 male, 136 female) who were diagnosed with beta thalassemia minor with high performance liquid chromatography (HPLC) method were enrolled in the study. Iron deficiency was detected in 17.52% of women and in 1.6% of men. Decreased vitamin B12 and folic acid values were detected as 28.7% and 10.3%, respectively. As the result of the study, it was concluded that serum iron and vitamin B12 levels should also be measured in assessment of TT patients due to its high prevalence in Mediterranean region. In addition, folic acid is recommended as folic acid deficiency may develop in some patients.
Beta thalassemia minor, iron deficiency anemia, vitamin B12, folic acid