Children suffering from lymphomas and solid tumors have acceptable outcome with current risk adapted multimodality treatment. Especially, in lymphomas overall survival rates have reached the 90% level or higher. Because of the rarity of randomized prospective trials on hematopoietic stem cell transplantation in children with solid tumors the EBMT registry remains an important source of information. Decisions for hematopoietic stem cell transplantation should ideally be based on prospective trials like in high-risk neuroblastoma. In this study, indications and results of the hematopoietic stem cell transplantation in children with solid tumors was reviewed shortly in light of current literature.
Hematopoietic stem cell transplantation, lymphomas, solid tumors, children