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BMMR. 2008; 11(2): 72-75


The effect of total mesorectal excision on local recurrence and distant metastasis in rectal cancer

Sucullu I, Filiz AI, Kurt Y, Coskun M, Akin ML, Demirbas S.

Abstract
Local recurrence after curative resection
in rectal cancers is one of the most important problems
colorectal surgeons encounter and struggle with
until today. While the local recurrence rate after
conservative curative surgery is between 11.7 and
37.6%, after total mesorectal excicion (TME) it is
between 1.6 and 17.8%.We aimed to evaluate the
effect of TME technique on local recurrence and
distant metastasis rates in rectal cancer patients
operated on either with TME technique or conventional
approaches during the past 10 years in a retrograde
study. Sixty-three patients included into this
study. The patients are divided into two follow-up
groups covering the first five years (first group, conventional
radical rectal excision period) and second
five years (second group, TME application period)
periods. There were 29 patients (median age of 58
years) in the first and 34 patients in the second (median
age of 62 years) group. After 2 years of followup,
the local recurrence rates were 20.7% (6 patients)
in the first and 11.8% (4 patients) in the second
group. Metastatic disease was observed in 8
patients (27.6%) in the first group and 7 (20.5%) in
the second group. It is concluded that TME is a
method easily applied and may be effective in reducing
the local recurrence and distant metastasis rates.

Key words: Rectal cancer, local recurrence, distant metastasis, mesorectal excision



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