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IJHSR. 2013; 3(12): 42-47


Intraperitoneal Instillation: Ropivacaine Vs Bupivacaine For Post Operative Pain Relief In Laparoscopic Cholecystectomy.

Rakesh Babu, Prithi Jain, Lulu Sherif.

Abstract
Objective: To compare the post operative pain scores after intraperitoneal instillation of 0.20% Ropivacaine with 0.25% Bupivacaine in patients undergoing laparoscopic cholecystectomy.
Methods: 60 elective cases posted for Laparoscopic cholecystectomy were included in the study. All patients were premedicated. Patients were given standard general anaesthesia. They were randomised into two groups. Group A: Patients received 20 ml of 0.2% ropivacaine (n = 30).Group B: Patients received 20 ml of 0.25% Bupivacaine (n =30) intraperitoneally at the end of surgery. Post operative pain was assessed with ten point VAS.
Statistical method: ANOVA test was used to compare the VAS in both the groups
Results: The age and sex distribution of both the groups was similar. The heart rate, systolic & diastolic blood pressure, mean blood pressure and mean trend of SpO2 in both groups remained similar over the periods. There is a significant reduction in VAS over the 12 hour period in both the treatment groups. No statistically significant adverse effects were noted. Duration of hospital stay was also similar in both the study groups.
Conclusion: Intraperitoneal instillation of ropivacaine or bupivacaine is an effective method of post op pain relief in laparoscopic cholecystectomy. Both these drugs significantly reduced the post op pain .We conclude that intraperitoneal instillation of local anaesthetic is an easy, cheap, and non-invasive method which provides good analgesia in the immediate postoperative period after laparoscopic cholecystectomy. Ropivacaine in view of better cardiovascular safety profile can be an effective alternative for Bupivacaine, with similar post operative pain relief.

Key words: Ropivacaine, Bupivacaine, laparoscopic cholecystectomy, post operative pain



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