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Gulhane Med J. 2009; 51(4): 251-253

The effect of somatostatin in the treatment of neoplastic chylothorax

Orhan Yücel1, Alper Gözübüyük1, Sedat Gürkök1, Ersin Sapmaz1, Mustafa Öztürk2, Onur Genç1.

Chylothorax is the accumulation of lymphatic fluid within the pleural space. Chylothorax can occur in various clinical settings and arise from diverse causes. The optimal management of the patients with chylothorax is still uncertain. Treatment of chylothothorax can be divided into conservative therapy, operative therapy and radiation therapy. Recent reports have suggested that octreotide, by value of its direct action on lymphatic flow, has been useful in resolution of neoplastic chylothorax in the adult population. We herein report prompt cessation of lymphorrhea in an adult patient with chylothorax using octreotide, a long-acting somatostatin analog.

Key words: Chylothorax, neoplastic chylothorax, octreotide, somatostatin

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