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RMJ. 2011; 36(3): 178-181


Microbial Infections in females of childbearing age and therapeutic interventions

Fouzia Zeeshan Khan.

Abstract
Introduction: Infectious vaginitis is the most common problem among females in our country. It includes Trichomoniasis and Bacterial vaginosis.
Objective: The objective of this study was to determine the incidence and etiology of microbial infections of vagina in women of child bearing age and their therapeutic intervention.
Material and Methods: 100 high vaginal swabs were collected from patients and clinical history was recorded. Trichomonas vaginalis was identified on wet mount. High vaginal swabs were inoculated on selective and differential media. Identification was done by standard method. Clue cells pathognomic of Gardnerella vaginalis were identified on wet mount. For G.vaginalis, vaginal swabs were inoculated on human bilayer media. Antibiotic susceptibility was done by disc diffusion method
Results: Vaginal infections were present in females in 20-39 years of age. Non-pregnant female patients were 88% and pregnant female 12%. Polymicrobial infection was detected in 25 (10%) of cases. T.vaginalis was present in 20% of cases. Bacteria isolated were G.vaginalis 30%, group B Streptococci 20% and group D Streptococci 5%. Amoxycillin/clavulanic acid, cephalosporin, clindamycin, and metronidazole were effective against bacterial isolates.
Conclusion: Vaginal infections were present in females in 20-39 years of age. T.vaginalis was present in some of the cases. G.vaginalis was second most common causative agent isolated from high vaginal swabs. Amoxycillin /clavulanic acid, metronidazole, clindamycin and cephalexin were effective against G.vaginalis.

Key words: Bacterial vaginosis, Gardnerella vaginalis, Trichomonas vaginalis



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