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Acta Inform Med. 2011; 19(1): 16-18

Assessment of Lung Dysfunction with Spirometry in Patients with Thyroid Disorders

Salih Valjevac, Almira Hadzovic-Dzuvo, Amina Valjevac, Elma Kucukalic-Selimovic, Orhan Lepara.

Thyroid hormones might lead to significant decrease in pulmonary ventilation in patients with dysfunctional thyroid disorders. The aim of the study was to assess the pulmonary ventilation in patients with thyroid dysfunctional states. This observational, cross-sectional study included 20 patients with hyperthyroidism, 20 patients with hypothyroidism and 20 euthyroid subjects. Serum FT3, FT4 and TSH levels were determined with the ElectroChemiLuminiscent immunoassay. Spirometry analysis was performed on portable spirometer SpiroUSB using the software Spida 5 for the analysis. We determined VC%, FVC%, FEV1% and FVC/ FEV1% Mean VC% was significantly lower in hyperthyroid (94,181,24%) and hypothyroid (96,131,09%) compared to euthyroid group of subjects (98,540,93%)(p

Key words: thyroid dysfunction, spirometry, lung function

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