A comparative efficacy of Prestokon® and Furazine-II® in the treatment of microbial diarrhea in neonatal lambs over a 24 hour period was evaluated. Microbial Colony Forming Units (CFU) per gram of each faecal sample was determined before treatment and 24 hours after treatment, specific causative microorganisms were not isolated. The average total CFU / g of faeces killed within 24 hours by Prestokon® was 63.31+ 6.22 % and 32.47+14.75 % for Furazine-II®. The clinical response to treatment was also significantly (P < 0.01) better in lambs treated with Prestokon®. Although the result of this study suggest that Prestokon® might be more effective in the treatment of microbial diarrhea in lambs, it must be pointed out that clinically both drugs can be given repeatedly over a period of several days until clinical cure or improvement was observed.
Microbial diarrhea, neonatal lambs, treatment.